2-(Chloromethyl)-4-methoxy-3-methylpyridine--hydrogen chloride (1/1) → HCID 14575168, compound

HRID 1085064Notes

Reaction equation

[SH:1][C:2]1[N:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[C:10](=[O:20])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH3:21])[CH:8]=2)[N:3]=1.Cl.Cl[CH2:24][C:25]1[C:30]([CH3:31])=[C:29]([O:32][CH3:33])[CH:28]=[CH:27][N:26]=1>>[CH3:33][O:32][C:29]1[CH:28]=[CH:27][N:26]=[C:25]([CH2:24][S:1][C:2]2[N:11]([C:12]3[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[C:10](=[O:20])[C:9]3[C:4](=[CH:5][CH:6]=[C:7]([CH3:21])[CH:8]=3)[N:3]=2)[C:30]=1[CH3:31]

Participants

Reactant 2

HCID 115139822-(Chloromethyl)-4-methoxy-3-methylpyridine--hydrogen chloride (1/1)

HCID 178492048HCID 178492048, compound

Product 1

HCID 14575168HCID 14575168, compoundYield 51.6%

Procedure

The title compound was prepared in a yield of 51.6%, using 2-mercapto-3-(4-methoxyphenyl)-6-methyl-4(3H)-quinazolinone in place of 2-mercapto-6-methyl-3-phenyl-4(3H)-quinazolinone and 2-chloromethyl-4-methoxy-3-methylpyridine hydrochloride in place of 2-chloromethylpyridine hydrochloride.

Sources & evidence

ORD record: ord-208ee52eb9884329a65748dc42155965
Source dataset: uspto-grants-1991_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05008266

Reaction notes

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