Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085064Generated: October 31, 2026

2-(Chloromethyl)-4-methoxy-3-methylpyridine--hydrogen chloride (1/1) → 2-[(4-Methoxy-3-methylpyridin-2-yl)methylthio]-3-(4-methoxyphenyl)-6-methyl-4(3H)-quinazolinone

https://huagongshe.com/reaction/1085064

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-4-methoxy-3-methylpyridine--hydrogen chloride (1/1)HCID 11513982—
ReactantHCID 178492048HCID 178492048—
Product2-[(4-Methoxy-3-methylpyridin-2-yl)methylthio]-3-(4-methoxyphenyl)-6-methyl-4(3H)-quinazolinoneHCID 1457516851.6%

Reaction Steps

The title compound was prepared in a yield of 51.6%, using 2-mercapto-3-(4-methoxyphenyl)-6-methyl-4(3H)-quinazolinone in place of 2-mercapto-6-methyl-3-phenyl-4(3H)-quinazolinone and 2-chloromethyl-4-methoxy-3-methylpyridine hydrochloride in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-208ee52eb9884329a65748dc42155965
Source noteuspto-grants-1991_04