Hydrogen Bromide → HCID 20061587, compound

HRID 1085120Notes

Reaction equation

HRID 1085120 reaction equation
Cl.C([S:6][CH2:7][CH2:8][N:9]1[C:13]2[CH:14]=[CH:15][C:16]([O:18][C:19]([F:22])([F:21])[F:20])=[CH:17][C:12]=2[S:11][C:10]1=[NH:23])(C)(C)C.[BrH:24]>>[BrH:24].[NH:23]=[C:10]1[N:9]([CH2:8][CH2:7][SH:6])[C:13]2[CH:14]=[CH:15][C:16]([O:18][C:19]([F:22])([F:20])[F:21])=[CH:17][C:12]=2[S:11]1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 14674477HCID 14674477, compound

Product 1

HCID 20061587HCID 20061587, compound

Conditions

Temperature
0 °C

Procedure

3-(2-tert-Butylthioethyl)-2-imino-6-trifluoromethoxybenzothiazoline hydrochloride (1.5 g) and 47% strength hydrobromic acid (15 cc) are heated for 4 hours to 100° C. After cooling of the mixture to 0° C., the precipitate formed is filtered off and washed with distilled water (2×25 cc) and then with ethyl ether (2×30 cc). 2-(2-Imino-6-trifluoromethoxy-3-benzothiazolinyl)ethanethiol hydrobromide (0.9 g), m.p. 180° C., is obtained.

Workup

  1. customthe precipitate formed
  2. filtrationis filtered off
  3. washwashed with distilled water (2×25 cc)

Sources & evidence

ORD record
ord-271f7c3129ce4e0dbaa8a948ba53ea44
Source dataset
uspto-grants-1991_04
Patent number
US05008280

Reaction notes

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