m-Chloroperbenzoic acid → HCID 20061596, compound

HRID 1085121Notes

Reaction equation

HRID 1085121 reaction equation
[NH:1]=[C:2]1[N:6]([CH2:7][CH2:8][S:9][CH3:10])[C:5]2[CH:11]=[CH:12][C:13]([O:15][C:16]([F:19])([F:18])[F:17])=[CH:14][C:4]=2[S:3]1.[Cl:20]C1C=CC=C(C(OO)=[O:28])C=1>C(O)C>[ClH:20].[NH:1]=[C:2]1[N:6]([CH2:7][CH2:8][S:9]([CH3:10])=[O:28])[C:5]2[CH:11]=[CH:12][C:13]([O:15][C:16]([F:19])([F:17])[F:18])=[CH:14][C:4]=2[S:3]1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 14674476HCID 14674476, compound

Product 1

HCID 20061596HCID 20061596, compoundYield 34.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The procedure is as in Example 8, starting with 2-imino-3-(2-methylthioethyl)-6-trifluoromethoxybenzothiazoline (3.7 g) and m-chloroperbenzoic acid (2.3 g) in absolute ethanol (60 cc). After 30 minutes at -20° C., the precipitate formed is filtered off and the hydro-chloride prepared in acetone (60 cc). (RS)-2-Imino-3-(2-methylsulphinylethyl)-6-trifluoromethoxybenzo-thiazoline hydrochloride (1.5 g), m.p. 186° C., is obtained.

Workup

  1. customthe precipitate formed
  2. filtrationis filtered off
  3. customthe hydro-chloride prepared in acetone (60 cc)

Sources & evidence

ORD record
ord-9dfb09c04af64907a091d75afe5a8f93
Source dataset
uspto-grants-1991_04
Patent number
US05008280

Reaction notes

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