Hydrochloric Acid → HCID 11034267, compound

HRID 1085374Notes

Reaction equation

HRID 1085374 reaction equation
[CH2:1]([CH:4]1[CH2:9][CH2:8][C:7](=[O:10])[CH2:6][CH2:5]1)[CH2:2][CH3:3].[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.Cl.O>C1(C)C=CC=CC=1>[OH:10][C:7]1[CH:8]=[CH:9][C:4]([C:1]2([C:14]3[CH:15]=[CH:16][C:11]([OH:17])=[CH:12][CH:13]=3)[CH2:3][CH2:2][CH:1]([CH2:4][CH2:5][CH3:6])[CH2:3][CH2:2]2)=[CH:5][CH:6]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 996PhenolHCID 1424824-Propylcyclohexanone

Product 1

HCID 11034267HCID 11034267, compoundYield 91.5%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

1st stage 4-n-Propylcyclohexanone 650 g and phenol 1550 g were mixed, and hydrochloric acid gas was blown to the mixture with vigorously stirring at room temperature. The mixture was vigorously stirred for three hours and then left for 50 hours at room temperature. Meantime, the reaction solution was solidified. Warm water 1,000 ml and toluene 3,000 ml were added to the solid. The solid was heated and dissolved completely. The crystals deposited from the solution after cooling were filtered and washed with water and with toluene. After drying the crystals, white crystals 658 g of 1,1-bis(4-hydroxyphenyl)-4-n-propylcyclohexane was obtained by recrystallization from acetone.

Workup

  1. stirringThe mixture was vigorously stirred for three hours
  2. temperatureThe solid was heated
  3. dissolutiondissolved completely
  4. temperatureafter cooling
  5. filtrationwere filtered
  6. washwashed with water and with toluene
  7. customAfter drying the crystals

Sources & evidence

ORD record
ord-24d1a5df55ba4dea8eb3d41b363f3ae1
Source dataset
uspto-grants-1991_04
Patent number
US05008456

Reaction notes

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