HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1-Naphthyl)piperazine → 3-Ethylthio-5-fluoro-3-(2-[4-(1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1-Naphthyl)piperazine | HCID 1342 | — |
| Reactant | 3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl)-1,3-dihydro-2(2H)-indolone tosylate | HCID 14601168 | — |
| Product | 3-Ethylthio-5-fluoro-3-(2-[4-(1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone | HCID 14601182 | — |
Reaction Steps
The product is obtained by following the procedure described under 1.3, starting with 31.6 g (0.148 mole) of 1-naphthylpiperazine and 30.5 g (0.074 mole) of 3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl) -1,3-dihydro-2(2H)-indolone tosylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05010079 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-1b04e9ea888d4a12a0df5908be4eb0ba |
| Source note | uspto-grants-1991_04 |