Cyanogen Bromide → HCID 15107886, compound

Participants

Reaction Steps

A 46.88 gm (0.236 mole) quantity of 1-chloro-4-hydrazino5,6,7,8-tetrahydrophthalazine was added to 450 ml of methanol. A 40.8 gm quantity of sodium acetate and 25.0 gm of cyanogen bromide was added and the mixture was stirred on a warm plate for 30 minutes. Yellow crystals appeared immediately. The mixture was allowed to sit for 3 days. The resulting solid was filtered, washed with ether, and dried, yielding 44.85 gm of 3-amino-6-chloro-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine; mp 224-225° C. (ethanol).

Provenance & Evidence