Morpholine → HCID 15107893, compound

Participants

Reaction Steps

A 22.40 gm (0.100 mole) quantity of 3-amino-6-chloro-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine was added to 225 ml of morpholine and the mixture was refluxed for 7 hours. The mixture was then evaporated. A 250 ml volume of water was added to the residue and the mixture was stirred. The resulting solid was filtered and dried, yielding 27.2 gm of 3-amino-6-(4-morpholinyl)-7,8,9,10-tetrahydro-1,2,4triazolo [3,4-a]phthalazine; mp 260-262° C.

Provenance & Evidence