反应详情

温度

25 °C

13.0 g (0.22 mol) of n-propylamine were added at -20° C. to a mixture of 13.4 g (0.1 mol) of 2,4,6-trifluoropyrimidine in 150 ml of diethyl ether within 20 minutes. After stirring at -20° C. for 1 hour and at 25° C. for 1 hour, the precipitate was filtered off, and the organic phase was washed with water, dried and concentrated under reduced pressure. 15.8 g (91.3% of theory) of the title compound were obtained as an oil (nD23 =1.4965).

1. filtrationthe precipitate was filtered off
2. washthe organic phase was washed with water
3. customdried
4. concentrationconcentrated under reduced pressure