HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbohydrazide → Cyclopropanecarboxylic acid [1-(6-chloro-3-pyridinyl)ethylidene]hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbohydrazide | HCID 81396 | — |
| Reactant | 1-(6-Chloropyridin-3-yl)ethan-1-one | HCID 2779698 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Cyclopropanecarboxylic acid [1-(6-chloro-3-pyridinyl)ethylidene]hydrazide | HCID 53866309 | — |
Reaction Steps
Following the general method of procedure 53 and making non-critical variations, except the product was purified by recrystallization from absolute ethanol rather than by chromatography, 5.25 gm (0.0337 mole) of 3-acetyl-6-chloropyridine and 3.40 gm (0.034 mole) of cyclopropanecarboxylic acid hydrazide yield 6.52 gm (81%) of the title compound having a melting point of 218.1° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05011932 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-3e26f3baca9f4c03be0fc3a931816e59 |
| Source note | uspto-grants-1991_04 |