Ethanol → HCID 131716843, compound

HRID 1086001Notes

Reaction equation

HRID 1086001 reaction equation
[CH3:1][C:2]([NH:5][CH2:6][C:7]1[C:12]([CH2:13][OH:14])=[C:11]([OH:15])[CH:10]=[CH:9][C:8]=1[CH2:16][OH:17])([CH3:4])[CH3:3].[S:18](=[O:22])(=[O:21])([OH:20])[OH:19].C(O)C>O>[S:18]([OH:22])([OH:21])(=[O:20])=[O:19].[CH3:4][C:2]([NH:5][CH2:6][C:7]1[C:12]([CH2:13][OH:14])=[C:11]([OH:15])[CH:10]=[CH:9][C:8]=1[CH2:16][OH:17])([CH3:1])[CH3:3].[CH3:4][C:2]([NH:5][CH2:6][C:7]1[C:12]([CH2:13][OH:14])=[C:11]([OH:15])[CH:10]=[CH:9][C:8]=1[CH2:16][OH:17])([CH3:1])[CH3:3]

Participants

5

Reactant 3

HCID 702Ethanol2×HCID 1118Sulfuric AcidHCID 21937281HCID 21937281, compound

Product 1

HCID 131716843HCID 131716843, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

α1 -[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol (5.8 g) is dissolved in deionized water (8 ml) containing concentrated sulfuric acid (0.68 ml). The solution is stirred for 60 minutes, treated with ethanol (60 ml), stirred for 18 hours, treated with a further portion of ethanol (60 ml) and the title compound (3.35 g) isolated by filtration as a white powder.

Workup

  1. stirringstirred for 18 hours

Sources & evidence

ORD record
ord-8dbcf48eb2cd46c4844392ffe6eebcf2
Source dataset
uspto-grants-1991_04
Patent number
US05011993

Reaction notes

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