HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylmorpholine → HCID 178476288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylmorpholine | HCID 7525 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 3-((1,1-dimethylethyl)dithio)-N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-alanine | HCID 16213190 | — |
| Reactant | HCID 178451187 | HCID 178451187 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178476288 | HCID 178476288 | — |
Reaction Steps
2.2 g of DCC are added, at 0° C., to a stirred solution of 4.31 g (10 mmol) of Fmoc-Cys(StBu)--OH, 7.74 g of H-Arg-Phe-OtBu.2 HClO4 (oily substance obtained above), 1.35 g of HOBt and 1.3 ml of N-ethylmorpholine in 40 ml of dimethylformamide. The mixture is worked up in analogy to Example 1a. The residue is triturated with diethyl ether and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05011825 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-b79d3db985854d78a22a96c125945c3f |
| Source note | uspto-grants-1991_04 |