HCID 19826884, compound → HCID 19826893, compound

Participants

Reaction Steps

A mixture of 1,3-dichloro-6-methyl-4-phenyl-5,6,7,8-tetrahydro-4H-thieno[3,4-d]azepine (73 mg) and 10% palladium on carbon (20 mg) in acetic acid (2 ml) was hydrogenated for 24 hours at 60 p.s.i. The mixture was filtered and the filtrate evaporated to a yellow oil. Chromatography on silica (1% methanol-ammonia in dichloromethane) gave the title product as an oil.

Provenance & Evidence