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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1086173Generated: November 1, 2026

Ethylamine → HCID 14207595, compound

https://huagongshe.com/reaction/1086173

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
ReactantHCID 14207621HCID 14207621—
ProductHCID 14207595HCID 14207595—

Reaction Steps

A solution of 1.5 g (9.8 mmol) of 5,8-dichloroimidazo[ 1,2-a]pyrazine in 25 ml of a 40% strength aqueous ethylamine solution is maintained with stirring for 12 hours. After concentration under reduced pressure and chromatography on a silica column (eluant=ether), 5-chloro-8-ethylaminoimidazo[1,2-a]pyrazine (m.p. 94° C.), is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05028605
Source datasetuspto-grants-1991_07
ORD IDord-49779614ad9446ab9106858460f94bd4
Source noteuspto-grants-1991_07