HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromodiphenylmethane → 1-Diphenylmethyloxy-5 p-methoxybenzyloxy-2-hydroxymethyl-4-pyridone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromodiphenylmethane | HCID 236603 | — |
| Reactant | 5-p-Methoxybenzyloxy-1-hydroxy-2-hydroxymethyl-4-pyridone | HCID 10707645 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Diphenylmethyloxy-5 p-methoxybenzyloxy-2-hydroxymethyl-4-pyridone | HCID 15627767 | — |
Reaction Steps
5.54 g of 5-p-methoxybenzyloxy-1-hydroxy-2-hydroxymethyl-4-pyridone is suspended in 40 ml of N,N-dimethylformamide, and then 2.24 g of potassium t-butoxide is added with ice cooling to dissolve. 4.94 g of benzhydryl bromide is added thereto and reacted at room temperature for 2.5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05028601 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-01ec7d369000442991c48903b05c3433 |
| Source note | uspto-grants-1991_07 |