反应详情

A mixture of 1.84 g of 3-benzyl-2-cyanoiminothiazolidine and 10 ml of hydrazine monohydrate was heated at reflux under an algon atmosphere for an hour. After the reaction, the solvent was evaporated under reduced pressure, and the residue was recrystallized from ethanol to give 2 g of 5-amino-3-[N-(2-mercaptoethyl)benzylamino]-1,2,4-triazole (Compound 1).

1. temperaturewas heated
2. temperatureat reflux under an algon atmosphere for an hour
3. customAfter the reaction
4. customthe solvent was evaporated under reduced pressure
5. customthe residue was recrystallized from ethanol