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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1086346Generated: November 1, 2026

Tetrahydrofuran → HCID 12218047, compound

https://huagongshe.com/reaction/1086346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 13065771HCID 13065771—
ProductHCID 12218047HCID 1221804711%

Reaction Steps

Example 14 was repeated except that 4.0 ml (9.0 mmoles) of a 2.25N aqueous solution of potassium hydroxide was used instead of lithium hydroxide as a base, and 8 ml of tetrahydrofuran was used as a solvent. A mixture of 2-oxo-3-phenylbutanoic acid (65 %) and 2-oxo-3-methyl-3-phenylbutanoic acid (11 %) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05028738
Source datasetuspto-grants-1991_07
ORD IDord-f9e52d5aa848434d9d29fbb3b264dcf2
Source noteuspto-grants-1991_07