3-Bromobenzoic acid → Benzoyl chloride, 3-bromo-

HRID 1086372Notes

Reaction equation

HRID 1086372 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5](O)=[O:6].S(Cl)([Cl:13])=O>C(Cl)(Cl)Cl>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([Cl:13])=[O:6]

Participants

4

Reactant 2

HCID 114563-Bromobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 74377Benzoyl chloride, 3-bromo-

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To CHCl3 is added 3-bromobenzoic acid (100 g) and thionyl chloride (109 ml) and refluxed overnight. The remaining thionyl chloride is evaporated off to afford 3-bromobenzoic acid chloride.

Workup

  1. temperaturerefluxed overnight
  2. customThe remaining thionyl chloride is evaporated off

Sources & evidence

ORD record
ord-08fc04917caa495f8445d4a2a01c6a91
Source dataset
uspto-grants-1991_07
Patent number
US05028629

Reaction notes

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