Methanol → HCID 53939730, compound

HRID 1086377Notes

Reaction equation

HRID 1086377 reaction equation
CS[C:3]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:12][C:4]=1[CH:5]=[CH:6][C:7]([N:9]([OH:11])[CH3:10])=[O:8].O[O:26][S:27]([O-:29])=O.[K+].[CH3:31]O>O>[CH3:31][S:27]([C:3]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:12][C:4]=1[CH:5]=[CH:6][C:7]([N:9]([OH:11])[CH3:10])=[O:8])(=[O:29])=[O:26]

Participants

5

Reactant 3

HCID 887Methanol2×HCID 23707502Potassium hydroxy sulfiteHCID 54423125HCID 54423125, compound

Product 1

HCID 53939730HCID 53939730, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In methanol (15 ml) is placed 2-methylthio-5-(3-phenylpropyl)-N-hydroxy-N-methylcinnamamide (0.35 g, 1.02 mmol) prepared according to Example 27. In 3 ml of water is placed oxone (0.94 g, 1.54 mmol) which is added to the methanol solution and stirred at room temperature for 3 days. The reaction mixture is poured into 80 ml of water, then extracted twice with 75 ml portions of ethyl acetate. The organic layers are washed

Workup

  1. customprepared
  2. extractionextracted twice with 75 ml portions of ethyl acetate
  3. washThe organic layers are washed

Sources & evidence

ORD record
ord-d1a61b80c2634ceca8567c43005c5458
Source dataset
uspto-grants-1991_07
Patent number
US05028629

Reaction notes

Loading…