Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Butylamine | HCID 8007 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethane, 1-chloro-2-(ethylsulfonyl)- | HCID 101406 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 19818855 | HCID 19818855 | — |
Reaction Steps
A solution of 15.7 g of chloroethyl ethyl sulfone in 50 ml of toluene is added dropwise within 10 min to a solution of 73 g of n-butylamine and 10.1 g of triethylamine in 100 ml of toluene at an internal temperature of 50° C. The mixture is stirred at 50° C. for 5 h and allowed to cool to room temperature, the precipitate is filtered off with suction, and the filtrate is concentrated in a rotary evaporator. The remaining yellow oil (18.7 g) is reacted without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05030270 |
|---|
| Source dataset | uspto-grants-1991_07 |
|---|
| ORD ID | ord-b546acbb437146d58bfdb310fbcc1266 |
|---|
| Source note | uspto-grants-1991_07 |
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