HCID 14773690, compound → HCID 14773693, compound

HRID 1086414Notes

Reaction equation

HRID 1086414 reaction equation
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:12][C:11]([F:14])([F:13])[C:10]1=[O:15].[Cl-].[S:17](=[CH2:20])(=[O:19])=[O:18]>N1C(C)=CC=CC=1C.CCOCC>[CH3:20][S:17]([O:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:12][C:11]([F:13])([F:14])[C:10]1=[O:15])(=[O:19])=[O:18]

Participants

5

Reactant 2

HCID 14773690HCID 14773690, compoundHCID 23435324HCID 23435324, compound

Product 1

HCID 14773693HCID 14773693, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 79372,6-LutidineSolvent

Conditions

Temperature
7 °C

Procedure

0.17 mmole of compound 4a is dissolved in 0.8 ml of 2,6-lutidine at 0° C., followed by the addition of 0.18 mmole of sulphonyl methane chloride to said solution. After stirring the reaction mixture for 90 min. at a temperature of 4 to 10° C., the solution is taken up in 1 ml of ether and then washed twice with 0.5 ml of saturated aqueous NaCl solution.

Workup

  1. washwashed twice with 0.5 ml of saturated aqueous NaCl solution

Sources & evidence

ORD record
ord-5b77f508e8ab4303bbcac05f82b9d452
Source dataset
uspto-grants-1991_07
Patent number
US05030628

Reaction notes

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