反应详情

58.7 g (564.4 mmoles) of 2-(2-aminoethylamino)ethanol and 122.8 g (538.6 mmoles) of ethyl dodecanoate were heated at 125° C. and ethanol was removed by distillation. 100 ml of toluene was cautiously added and water was removed azeotropically on further reflux. The reaction mixture was fractionally distilled to give 100.2 g (69.5%) of pure product, m.p. 40°-42° C.

1. customethanol was removed by distillation
2. addition100 ml of toluene was cautiously added
3. customwater was removed azeotropically on further reflux
4. distillationThe reaction mixture was fractionally distilled