Ethyl Dodecanoate → HCID 15158289, compound

HRID 1086444Notes

Reaction equation

HRID 1086444 reaction equation
[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][NH:7][CH2:8][CH2:9][NH2:10].[C:11](OCC)(=O)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][N:7]1[CH2:8][CH2:9][N:10]=[C:22]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH3:11]

Participants

3

Reactant 2

HCID 7800Ethyl DodecanoateHCID 103294242-[2-(2-aminoethylamino)ethoxy]ethanol

Product 1

HCID 15158289HCID 15158289, compoundYield 50.7%

Procedure

13.7 g (92.6 mmoles) N-[2-(2-Hydroxyethoxy)ethyl]ethylenediamine and 19.6 g (86 mmoles) of ethyl dodecanoate were mixed and heated in a flask equipped with a Dean-Stark trap. After the separated ethanol and water were distilled off, the residue was kugelrohr distilled at 160°-170° C./0.1 mm to give 13.6 g (50.7%) of crude product. Recrystallization from ethyl acetate/hexane gave white crystalline material, m.p. 58°-60° C.

Workup

  1. temperatureheated in a flask
  2. customequipped with a Dean-Stark trap
  3. distillationAfter the separated ethanol and water were distilled off
  4. distillationthe residue was kugelrohr distilled at 160°-170° C./0.1 mm

Sources & evidence

ORD record
ord-8e006792af9646799a84c0f34df1c2fd
Source dataset
uspto-grants-1991_07
Patent number
US05030629

Reaction notes

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