反应详情

Acryloyl chloride (4.52 g, 0.05 mole) was added dropwise to a stirring solution of triethylamine (30 ml) and 2-β-methylaminoethyl)pyridine (6.81 g, 0.05 mole) in ethyl ether (500 ml). After stirring overnight at room temperature, the white solid was removed by filtration and washed well with ethyl ether. The organic phases were combined, dried over sodium sulfate, filtered then concentrated to dryness to give an orange oil. The structure was confirmed by NMR.

1. customthe white solid was removed by filtration
2. washwashed well with ethyl ether
3. dry with materialdried over sodium sulfate
4. filtrationfiltered
5. concentrationthen concentrated to dryness
6. customto give an orange oil