Acryloyl chloride → HCID 19826117, compound

HRID 1086459Notes

Reaction equation

HRID 1086459 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][NH:8][CH2:9][CH3:10])=[CH:3][CH:2]=1.[C:11](Cl)(=[O:14])[CH:12]=[CH2:13]>C(N(CC)CC)C>[CH2:9]([N:8]([CH2:7][C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1)[C:11](=[O:14])[CH:12]=[CH2:13])[CH3:10]

Participants

4

Reactant 2

HCID 13140Acryloyl chlorideHCID 96681N-Ethylpyridine-4-methylamine

Product 1

HCID 19826117HCID 19826117, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Following the method of Example 3, 4-picolyl ethylamine (4.27 g, 0.035 mole) was reacted with acryloyl chloride (3.15 g, 0.035 mole) and triethylamine (21 ml) and purified by chromatography on silica. Analysis calc. for C8H12N2 (136.20): Calc.: C, 69.44; H, 7.92; N, 14.72. Found: C, 69.26; H, 7.56; N, 14.59.

Workup

  1. custompurified by chromatography on silica

Sources & evidence

ORD record
ord-48c5a99a799b4dbdb63ed5a5bfe2d7a1
Source dataset
uspto-grants-1991_07
Patent number
US05030642

Reaction notes

Loading…