4-Toluenesulfonyl chloride → (+/-)-[6-Fluoro-7-(2-chlorophenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate

HRID 108647Notes

Reaction equation

HRID 108647 reaction equation
[Cl:1][c:2]1[c:3](-[c:8]2[c:9]([F:19])[cH:10][cH:11][c:12]3[c:16]2[O:15][CH:14]([CH2:17][OH:18])[CH2:13]3)[cH:4][cH:5][cH:6][cH:7]1.[c:20]1([CH3:30])[cH:21][cH:22][c:23]([S:26](=[O:27])(=[O:28])[Cl:29])[cH:24][cH:25]1>>[Cl:1][c:2]1[c:3](-[c:8]2[c:9]([F:19])[cH:10][cH:11][c:12]3[c:16]2[O:15][CH:14]([CH2:17][O:18][S:26]([c:23]2[cH:22][cH:21][c:20]([CH3:30])[cH:25][cH:24]2)(=[O:27])=[O:28])[CH2:13]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 68966574(+/-)-[7-(2-Chlorophenyl)-6-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanol

Product 1

HCID 86599286(+/-)-[6-Fluoro-7-(2-chlorophenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate

Sources & evidence

ORD record
ord-9dc2c5352e4748e4aa39ce7aa270709f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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