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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1086520Generated: November 1, 2026

4-Chlorobenzenesulfonyl chloride → 2-[N-[2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetyl-N-methylamino]-acetic acid

https://huagongshe.com/reaction/1086520

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzenesulfonyl chlorideHCID 7398—
ReactantGlycine, N-methyl-, methyl ester, hydrochloride (1:1)HCID 83544—
ReactantMethyl (2-aminoindan-5-yl)acetate hydrochlorideHCID 23359670—
Product2-[N-[2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetyl-N-methylamino]-acetic acidHCID 14883982—

Reaction Steps

In the same manner as described in Examples 24 and 33, methyl (2-aminoindan-5-yl)acetate hydrochloride, 4-chlorophenylsulfonyl chloride and methyl N-methyl-glycinate hydrochloride are treated to give 2-[N-[2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetyl-N-methylamino]-acetic acid

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05030652
Source datasetuspto-grants-1991_07
ORD IDord-7bf9697d0616420c85c3b2af21eb3d1c
Source noteuspto-grants-1991_07