Sodium Hydroxide → HCID 53656916, compound

Participants

Reaction Steps

1 g of the product of Step D were dissolved in 10 ml of ethanol and 5.1 ml of a 2N solution of sodium hydroxide were added. The mixture was stirred for 16 hours at ambient temperature and the mixture was evaporated to dryness under reduced pressure. The product obtained was neutralized with resin Dowex 50 W×8 and the fractions containing the desired product were evaporated to dryness. A product was obtained which was lyophilized in 150 ml of filtered, double distilled water to obtain 660 mg of the expected product with a Rf=0.5 in a BuOH--AcOH--H2O mixture (4-2-2).

Provenance & Evidence