Hydrochloric Acid → HCID 15730184, compound

HRID 1086596Notes

Reaction equation

HRID 1086596 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([S:12]([OH:15])(=[O:14])=[O:13])[C:10]=1[OH:11])[C:5]([OH:7])=[O:6].[K].Cl.[CH3:18]O>>[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([S:12]([OH:15])(=[O:13])=[O:14])[C:10]=1[OH:11])[C:5]([O:7][CH3:18])=[O:6]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 5462222PotassiumHCID 15730183HCID 15730183, compound

Product 1

HCID 15730184HCID 15730184, compound

Conditions

Temperature
0 °C

Procedure

3,4-Dihydroxy-5-sulfobenzoic acid, monopotassium salt (10.0 g, 36.7 mmoles) was slurried in 300 ml of dry methanol, cooled to 0° C., and treated for five minutes with dry hydrogen chloride. The resulting solution was allowed to warm to room temperature and was stirred for 48 hours. The mixture was filtered and the volatile materials were removed in vacuo. The resulting solid was dried in vacuo at 60° C. to give the title compound, 8.51 g, m.p. 116° C.

Workup

  1. temperatureto warm to room temperature
  2. filtrationThe mixture was filtered
  3. customthe volatile materials were removed in vacuo
  4. customThe resulting solid was dried in vacuo at 60° C.

Sources & evidence

ORD record
ord-f5d25980a7d44cd98940e39b84e9db92
Source dataset
uspto-grants-1991_07
Patent number
US05030724

Reaction notes

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