化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 2-chloro-1,3-thiazole-5-carboxylate → methyl 7-methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-chloro-1,3-thiazole-5-carboxylate | HCID 12897294 | — |
| 反応物 | 2-Amino-5-methoxybenzamide | HCID 20338217 | — |
| 生成物 | methyl 7-methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylate | HCID 15569301 | — |
反応手順
16.5 g of 5-methoxyanthranilamide and 18.64 g of methyl 2-chlorothiazole-5-carboxylate were stirred for 11/2 hours at 160° C. After working up in the conventional manner 24.7 g (85%) of the above compound was obtained; m.p. 187°-192° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05030727 |
| 出典データセット | uspto-grants-1991_07 |
| ORD ID | ord-c8cd4fc5b6ef4aa5827a0137b1cd9e82 |
| 出典メモ | uspto-grants-1991_07 |