HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorothiazole → 9-fluoro-5H-thiazolo-(2,3-b)-quinazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorothiazole | HCID 76429 | — |
| Reactant | 2-Amino-3-fluorobenzamide | HCID 15256791 | — |
| Product | 9-fluoro-5H-thiazolo-(2,3-b)-quinazolin-5-one | HCID 13217034 | 79% |
Reaction Steps
15.4 g of 3-fluoroanthranilamide and 13.1 g of 2-chlorothiazole were stirred for 7 hours at 150° C. After working up in the conventional manner there was obtained 17.3 g (79%) of the above compound; m.p. 187°-189° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05030727 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-31aa38c7c1994a8a9269c5d5ac9a8908 |
| Source note | uspto-grants-1991_07 |