HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-6-fluorobenzamide → 2-methyl-6-fluoro-5H-thiazolo-(2,3-b)-quinazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-6-fluorobenzamide | HCID 2778939 | — |
| Reactant | 2-Chloro-5-methyl-1,3-thiazole | HCID 10997083 | — |
| Product | 2-methyl-6-fluoro-5H-thiazolo-(2,3-b)-quinazolin-5-one | HCID 14100440 | 83% |
Reaction Steps
10.8 g of 6-fluoroanthanilamide and 9.4 g of 2-chloro-5-methylthiazole were stirred for 7 hours at 150° C. After working up in the conventional manner there was obtained 13.5 g (83%) of the above compound; m.p. 245°-246° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05030727 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-1c97d44639d9428ea5415169bbf5b50a |
| Source note | uspto-grants-1991_07 |