反应详情

A mixture of 133 parts tolyltriazole, 79.3 parts n-butyraldehyde, 100.1 parts cyclohexanol and 1.3 parts paratoluene sulphonic acid is heated in 600 parts cyclohexane with simultaneous azeotropic removal of the water formed during the reaction. The reaction is complete after 2 hours. Upon cooling to ambient temperature, the reaction mixture is washed with dilute sodium carbonate solution, then with water and finally dried over anhydrous magnesium sulphate. The dried reaction mixture is filtered and evaporated under reduced pressure and then stripped under vacuum (100° C./4 Pa) to yield 262.9 parts (91.5 %) of 1-(1-cyclohexyloxybutyl) tolyltriazole as a yellow oil. The product is distilled at 175° C./8 Pa to yield a pale yellow oil.

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2. washthe reaction mixture is washed with dilute sodium carbonate solution
3. dry with materialwith water and finally dried over anhydrous magnesium sulphate
4. customThe dried reaction mixture
5. filtrationis filtered
6. customevaporated under reduced pressure
7. customstripped under vacuum (100° C./4 Pa)