HCID 54450054, compound → HCID 53864706, compound

HRID 1086804Notes

Reaction equation

HRID 1086804 reaction equation
[OH:1][C@H:2]1[CH2:6][CH:5]=[CH:4][C@H:3]1[NH:7][C:8]1[C:9]2[N:10]=[CH:11][N:12]([C:22]=2[N:23]=[CH:24][N:25]=1)[C@@H:13]1[O:21][C@H:18]([CH2:19][OH:20])[C@@H:16]([OH:17])[C@H:14]1[OH:15].[H][H]>[Pt].C(O)C>[OH:1][C@H:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[NH:7][C:8]1[C:9]2[N:10]=[CH:11][N:12]([C:22]=2[N:23]=[CH:24][N:25]=1)[C@@H:13]1[O:21][C@H:18]([CH2:19][OH:20])[C@@H:16]([OH:17])[C@H:14]1[OH:15]

Participants

5

Reactant 2

HCID 54450054HCID 54450054, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 53864706HCID 53864706, compoundYield 74.6%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 702EthanolSolvent

Procedure

A mixture of N-(cis-2-hydroxycyclopent-4-enyl)adenosine (1.6 g), 5% platinum on charcoal (0.3 g) and ethanol (80 ml) was stirred in the presence of hydrogen for 20 h. The resulting mixture was filtered and the filtrate was evaporated. The residue was dissolved in methanol (50 ml) and the solution was evaporated to yield the title compound (1.2 g) as a foam.

Workup

  1. filtrationThe resulting mixture was filtered
  2. customthe filtrate was evaporated
  3. dissolutionThe residue was dissolved in methanol (50 ml)
  4. customthe solution was evaporated

Sources & evidence

ORD record
ord-40ed1c976da34dc3be287fb190f1ec83
Source dataset
uspto-grants-1991_07
Patent number
US05032583

Reaction notes

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