Methyl iodide → HCID 14986888, compound

Participants

Reaction Steps

In DMF (20 ml) was dissolved 1-benzyl-6-butyl-3-propyl-1,2,3,4-tetrahydro-5H-imidazo [2',1':5,1]pyrazolo[3,4-d]pyrimidine-2,4-dione (0.5 g). To the solution were added, at room temperature, K2CO3 (0.5 g) and methyl iodide (0.5 g). The mixture was stirred for 8 hours and concentrated to dryness. To the residue was added water, then precipitating crystals were recrystallized from aqueous methanol to give colorless crystals (0.51 g, 98%), m.p. 139°-140° C.

Provenance & Evidence