7-Nitro-1-tetralone → 7-Amino-1,2,3,4-tetrahydronaphthalen-1-one

HRID 1086845Notes

Reaction equation

HRID 1086845 reaction equation
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][C:11]2=[O:14])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Ni]>[NH2:1][C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][C:11]2=[O:14])=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 384457-Nitro-1-tetralone

Product 1

HCID 3271777-Amino-1,2,3,4-tetrahydronaphthalen-1-one

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

A solution of 2 g (0.0105 mole) 7-nitro-1-tetralone in 120 ml ethanol was hydrogenated under <5 psi H2 pressure using Raney Ni as catalyst. The solution was filtered with the aid of super gel and concentrated under reduced pressure to give the 7-amino-1-tetralone.

Workup

  1. filtrationThe solution was filtered with the aid of super gel
  2. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-61fe34ea4363434b8cdd645cf320cbb4
Source dataset
uspto-grants-1991_07
Patent number
US05032598

Reaction notes

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