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HRID1086856

反应详情

EQUATION

反应方程式

HRID 1086856 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc2[nH]ccc2c1
HCID74280

Indole-5-carboxylic acid

C9H7NO2

结构：O=[N+]([O-])c1ccc(CCN2CCNCC2)cc1
HCID14985965

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1ccc2[nH]ccc2c1)N1CCN(CCc2ccc([N+](=O)[O-])cc2)CC1
HCID14986000

未命名化合物

PROCEDURE

实验过程

In the manner described in Example 24, indole-5-carboxylic acid (100 mg, 0.62 mmol) and 1-[2-(4-nitrophenyl)ethyl]piperazine (151 mg, 0.64 mmol) gave, after purification by flash column chromatography on silica gel, eluting with CH2Cl2 /MeOH/NH3 ; 95:5:0.5 and trituration with hexane/EtOAc, the piperazine (38 mg, 16%), mp 204°-206° C.

WORKUP

后处理

  1. customgave
  2. customafter purification by flash column chromatography on silica gel
  3. washeluting with CH2Cl2 /MeOH/NH3