HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4.5-Dibromothiophene-2-carboxylic acid-N-ethoxyamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | O-ethylhydroxylamine hydrochloride | HCID 76850 | — |
| Reactant | 4,5-Dibromothiophene-2-carbonyl chloride | HCID 13418987 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4.5-Dibromothiophene-2-carboxylic acid-N-ethoxyamide | HCID 14882404 | — |
Reaction Steps
At room temperature, 6.8 g of 4.5-dibromothiophene-2-carboxylic chloride is stirred, in portions, into 6.8 g of O-ethylhydroxylamine hydrochloride in 10 ml of pyridine and 80 ml of tetrahydrofuran. After 30 minutes, dilute hydrochloric acid was added, and the product was filtered off and washed with water. Yield: 5.8 g; m.p.: 117-119° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05034049 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-5baa1b073a42465887f7dd68d8191e47 |
| Source note | uspto-grants-1991_07 |