1-(Triphenylphosphoranylidene)acetone → HCID 54093442, compound

HRID 1086960Notes

Reaction equation

HRID 1086960 reaction equation
[C:1]([C:5]1[CH2:9][C:8]([CH:11]=O)([CH3:10])[O:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].C1(P(C2C=CC=CC=2)(C2C=CC=CC=2)=[CH:20][C:21](=[O:23])[CH3:22])C=CC=CC=1.COC(C)(C)C>ClCCl>[C:1]([C:5]1[CH2:9][C:8]([CH:11]=[CH:20][C:21](=[O:23])[CH3:22])([CH3:10])[O:7][N:6]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

5

Reactant 3

HCID 150381-(Triphenylphosphoranylidene)acetoneHCID 15413tert-Butyl methyl etherHCID 14834351HCID 14834351, compound

Product 1

HCID 54093442HCID 54093442, compoundYield 97.8%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

35.0 g (0.21 mole) of 3-tert-butyl-5-formyl-5-methylisoxazoline were added dropwise to a solution of 79 g (0.25 mole) of 1-triphenylphosphoranylidene-2-propanone in 200 ml of dichloromethane. The reaction mixture was kept at 40° C. for 8 hours and then stirred with tert-butyl methyl ether. The residue was filtered off under suction and the filtrate was evaporated down to give 43 g of a yellow oil which slowly crystallized.

Workup

  1. filtrationThe residue was filtered off under suction
  2. customthe filtrate was evaporated down

Sources & evidence

ORD record
ord-298acef7fc364788b7290aad8d4f6c66
Source dataset
uspto-grants-1991_07
Patent number
US05034047

Reaction notes

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