HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Anhydride → HCID 15036624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | 2-(4-Bromothiophen-2-yl)ethan-1-amine | HCID 15036615 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 15036624 | HCID 15036624 | — |
Reaction Steps
A mixture of 2(4-bromo-2-thienyl)-ethylamine (37 g) and phthalic anhydride (26.7 g) in glacial acetic acid (500 ml) is heated at reflux over 15 hours. It is concentrated at reduced pressure, the residue is triturated with ethanol and collected. The solid is recrystallized from ethanol to afford N-[2-(4-bromo-2-thienyl)ethyl]-phthalimide, m.p. 115°-117°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05034381 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-7bd6bd3c275d436181393f1d9f9095c2 |
| Source note | uspto-grants-1991_07 |