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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1087014Generated: October 30, 2026

2-Chloroadenosine → 2-(6-Amino-2-{2-[4-(2-cyclohexyl-ethyl)-phenyl]-ethylamino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

https://huagongshe.com/reaction/1087014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroadenosineHCID 8974—
Reactant2-[4-(2-Cyclohexyl-ethyl)-phenyl]-ethylamineHCID 15036641—
Product2-(6-Amino-2-{2-[4-(2-cyclohexyl-ethyl)-phenyl]-ethylamino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diolHCID 15036642—

Reaction Steps

Reaction of 2-chloroadenosine with p-(2-cyclohexylethyl)-phenethylamine as described in Example 14 gives 2-[2-(p-2-cyclohexylethyl-phenyl)-ethylamino]-adenosine, [alpha]D25 =-25.6° in DMSO, m.p. 154°-160°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05034381
Source datasetuspto-grants-1991_07
ORD IDord-59f2d1aecaf5447093d2c69d9f2dc7b0
Source noteuspto-grants-1991_07