反应详情

A mixture of N-ethyl-3-(2,4-difluorophenylthio)4-nitrobenzamide (0.92 g), iron powder (0.92 g) and ammonium chloride (92 mg) in ethanol (10 ml) and water (5 ml) was stirred and refluxed for 2 hours. The mixture was filtered and the filtrate was concentrated. The residue was dissolved in ethyl acetate, washed with water, dried, and evaporated to give an oil of N-ethyl4-amino-3-(2,4-difluorophenylthio)benzamide (0.85 g).

1. temperaturerefluxed for 2 hours
2. filtrationThe mixture was filtered
3. concentrationthe filtrate was concentrated
4. dissolutionThe residue was dissolved in ethyl acetate
5. washwashed with water
6. customdried
7. customevaporated