Methanol → HCID 178501589, compound

Participants

Reaction Steps

9.40 g (38.9 mmol) of 2-amino-3-(1H-imidazol-4-yl)butyric acid dihydrochloride are solved in 100 ml methanol. Dry HCl-gas is bubbled through the solution while heating under reflux for 4 hours. After cooling the excess hydrochloric acid is removed by evaporation in vacuo. Yield: 9.8 g (98%) methyl 2-amino-3-(1H-imidazol-4-yl)butyrate hydrochloride as an amorphous solid.

Provenance & Evidence