Acetic Anhydride → HCID 19816902, compound

HRID 1087375Notes

Reaction equation

HRID 1087375 reaction equation
[CH3:1][C:2]1([CH3:20])[N:7]=[C:6]([N:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]2=[O:14])[C:5]2[CH:15]=[C:16]([NH2:19])[CH:17]=[CH:18][C:4]=2[O:3]1.[C:21](OC(=O)C)(=[O:23])[CH3:22]>N1C=CC=CC=1>[CH3:1][C:2]1([CH3:20])[N:7]=[C:6]([N:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]2=[O:14])[C:5]2[CH:15]=[C:16]([NH:19][C:21](=[O:23])[CH3:22])[CH:17]=[CH:18][C:4]=2[O:3]1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 19816950HCID 19816950, compound

Product 1

HCID 19816902HCID 19816902, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A mixture of 1 g of 2,2-dimethyl-4-(2-oxo-1,2-dihydro-1-pyridyl)-6-amino-2H-1,3-benzoxazine, 10 ml of acetic anhydride and 10 ml of pyridine is left to stand at 20° for 16 hours. The mixture is evaporated, and the residue is purified by chromatography to give 2,2-dimethyl-4-(2-oxo-1,2-dihydro-1-pyridyl)-6-acetamido-2H-1,3-benzoxazine.

Workup

  1. waitis left
  2. customThe mixture is evaporated
  3. customthe residue is purified by chromatography

Sources & evidence

ORD record
ord-4ea0eccd5e004898912a8d51dced724d
Source dataset
uspto-grants-1991_07
Patent number
US05036068

Reaction notes

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