N-[2-[3-(1,2,3,6-Tetrahydro-1-methyl-4-pyridinyl)-1H-indol-5-yl]ethyl]methanesulphonamide → HCID 19817116, compound

HRID 1087410Notes

Reaction equation

HRID 1087410 reaction equation
[CH3:1][N:2]1[CH2:7][CH:6]=[C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([CH2:17][CH2:18][NH:19][S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=3)[NH:10][CH:9]=2)[CH2:4][CH2:3]1>Cl.[Pd]>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([CH2:17][CH2:18][NH:19][S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=3)[NH:10][CH:9]=2)[CH2:6][CH2:7]1

Participants

4

Reactant 1

HCID 19817118N-[2-[3-(1,2,3,6-Tetrahydro-1-methyl-4-pyridinyl)-1H-indol-5-yl]ethyl]methanesulphonamide

Product 1

HCID 19817116HCID 19817116, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 313Hydrochloric AcidSolvent

Procedure

The product of stage (ii) (1.00 g) in ethanolic hydrogen chloride (200 ml) was hydrogenated for 1 h over pre-reduced 10% palladium on carbon (50% paste with water, 1.00 g).

Sources & evidence

ORD record
ord-1fac3c3502044f9693b9f3aaef8724f3
Source dataset
uspto-grants-1991_07
Patent number
US05036078

Reaction notes

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