Benzo(d)thiazol-2-amine → HCID 1729135, compound

HRID 1087474Notes

Reaction equation

HRID 1087474 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH2:11]([O:13][CH2:14][C:15](Cl)=[O:16])[CH3:12]>N1C=CC=CC=1>[CH2:11]([O:13][CH2:14][C:15]([NH:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1)=[O:16])[CH3:12]

Participants

4

Reactant 2

HCID 8706Benzo(d)thiazol-2-amineHCID 84189Ethoxyacetyl chloride

Product 1

HCID 1729135HCID 1729135, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2-Aminobenzothiazole (4.5 g) is dissolved in pyridine (100 ml) and thereto is added dropwise ethoxyacetyl chloride (3.0 ml) at room temperature. After the mixture is stirred at room temperature for 2 hours, the solvent is distilled off. The resulting solids are washed with water, dried and recrystallized from a mixed solvent of diethyl ether/n-hexane to give the title compound (4.5 g) having the following physical properties.

Workup

  1. distillationthe solvent is distilled off
  2. washThe resulting solids are washed with water
  3. customdried
  4. customrecrystallized from a mixed solvent of diethyl ether/n-hexane

Sources & evidence

ORD record
ord-b0e829dc8ceb4d85b2cc57e04f441c14
Source dataset
uspto-grants-1991_07
Patent number
US05036086

Reaction notes

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