Ethoxyacetyl chloride

HCID 84189

Notes Reactions

Substructure search Find similar structures

Basic information

CAS: 14077-58-8
Standard SMILES: CCOCC(=O)Cl
InChIKey: ZPMWWAIBJJFPPQ-UHFFFAOYSA-N
Molecular formula: C4H7ClO2
Average molar mass: 122.55 g/mol
Monoisotopic mass: 122.01345714

Names & identifiers

Preferred name: Ethoxyacetyl chloride
IUPAC: 2-ethoxyacetyl chloride
English name: ethoxyacetyl chloride
Molecular formula: C4H7ClO2
Molecular weight: 122.55

Names & synonyms

2-ethoxyacetyl chloride14077-58-8Ethoxyacetyl chlorideEINECS 237-930-3DTXSID50161473RefChem:592719DTXCID5083964237-930-3Acetyl chloride, 2-ethoxy-Ethoxyacetylchloride2-Ethoxyacetylchlorideethoxy-acetyl chloride

Show more names

2-ethoxy-Acetyl chloroideETHYL 3,3-DIETHOXYPROPIONAethoxyacetyl chloride ISO 9001：2015 REACH2-Ethoxyacetyl chloride, stabilized with 0.3% Magnesium oxide2-Ethoxyacetyl chloride, 97%, stab. with 0.3% MagnesiuM oxide

MFCD11170566Iopromide Impurity 56Acetyl chloride,2-ethoxy-alpha-Ethoxyacetyl Chloride; Ethoxyacetic Acid Chloride;Ethoxy acetyl chlorideethoxyacetic acid chloridealpha-Ethoxyacetyl chloride(2-Ethoxy)-acetyl chloride

Database identifiers

CAS: 14077-58-8
PubChem CID: 84189
DTXSID: DTXSID50161473
UNII: B9R853DVA9
EC Number: 237-930-3
Nikkaji: J216.858H

Properties

Computed structural properties

XLogP: 1
Topological polar surface area: 26.3 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 2
Rotatable bonds: 3
Heavy atoms: 7
Formal charge: 0
Complexity: 62.7

Experimental & physicochemical properties

SpringerMaterials PropertiesOptical coefficient

Physicochemical properties

Boiling point: 124 ℃ · 124℃
Density: 1.119 · 1.119
refractive index: 1.4204 · 1.4204
Flash point: 45 ℃ · 45℃
solubility: Chloroform (Sparingly)
form: Oil
color: Colourless
Water Solubility: Insoluble in water.
Exposure limits: 10 mg/m3OSHA: · ACGIH: TWA 10 mg/m3OSHA: TWA 15 mg/m3NIOSH: IDLH 750 mg/m3
Stability: Moisture Sensitive
Symbol(GHS): 2 · GHS02,GHS05,GHS07
Signal word: Danger
Hazard statements: 226 · H226-H314-H318-H332
Precautionary statements: 210 · P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a
HazardClass: 8 · 8
HS Code: 2918999090 · 2918999090

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P234, P240, P241, P242, P243, P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P390, P403+P235, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Safety data

hs_code: 2918999090
Signal word: Danger
Symbol(GHS): GHS02,GHS05,GHS07
hazard_class: 8
Hazard statements: H226-H314-H318-H332
Precautionary statements: P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a

Chemistry & industry

Applications · 1 item

UsesIt is employed in fine chemical syntheses and used as pharmaceutical intermediates. A trace of cis-ethoxyacetamide was also detected and isolated with an authentic sample prepared from the reaction of cis-3-amino-6-methylchroman-4-01 (2) with 2-ethoxyacetyl chloride.