反应详情

Also prepared by the general method described in Example 6 utilizing phenyl cyclobutyl ketone, phenyl isopropyl ketone, phenyl methyl ketone and phenyl isobutyl ketone with the appropriate secondary amine were 1-cyclobutyl-1-hydroxy-1-phenyl-7-dimethylaminohept-5-yn-2-one, 1-cyclobutyl-1-hydroxy-1-phenyl-7-(N-ethyl-N-methylamino)hept-5-yn-2-one, 3-hydroxy-2-methyl-3-phenyl-9-dimethylaminonon-7-yn-4-one, 1-(1-methylcyclopropyl)-1-hydroxy-1-phenyl-7-dimethylaminohept-5-yn-2-one, and 4-hydroxy-2-methyl-4-phenyl-10-dimethylaminodec-8-yn-5-one.

1. customAlso prepared by the general method