Dichloromethane → HCID 19755541, compound

HRID 1087670Notes

Reaction equation

HRID 1087670 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([Cl:14])=[C:8]([S:10](Cl)(=[O:12])=[O:11])[CH:9]=1)([O-:3])=[O:2].ClCCl.[CH3:18][NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]>C(N(CC)CC)C>[CH3:18][N:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[S:10]([C:8]1[CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[CH:6][C:7]=1[Cl:14])(=[O:12])=[O:11]

Participants

5

Reactant 3

HCID 6344Dichloromethane2×HCID 206302-Chloro-5-nitrobenzenesulfonyl chlorideHCID 75539N-Methyloctadecylamine

Product 1

HCID 19755541HCID 19755541, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

44 g of 5-nitro-2-chlorobenzenesulfonylchloride and 100 ml of dichloromethane were mixed. A dichloromethane solution of 48.4 g of methyloctadecylamine and 36.1 ml of triethylamine was added dropwise to the mixture. After the reaction was completed, the reaction solvent was removed under reduced pressure. 300 ml of methanol was added to the reaction system so that dissolution was effected. The solution was then gradually allowed to cool. As a result, crystals precipitated. The crystals were filtered, and then dried.

Workup

  1. customthe reaction solvent was removed under reduced pressure
  2. addition300 ml of methanol was added to the reaction system so that dissolution
  3. temperatureto cool
  4. customAs a result, crystals precipitated
  5. filtrationThe crystals were filtered
  6. customdried

Sources & evidence

ORD record
ord-250a344dfc444ce1b247aaadc3f792fb
Source dataset
uspto-grants-1990_10
Patent number
USH0000830

Reaction notes

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