Sodium borohydride → HCID 14556343, compound

Participants

Reaction Steps

0.01 mole of 3-methyl-6-{3-[4-(3-trifluoromethylphenyl)-1-piperazinyl]-1-oxopropyl}benzoxazolinone is dissolved in 200 cm3 of methanol in a 250-cm3 flask equipped with a magnetic stirrer. 0.02 mole of sodium borohydride is added very slowly and with stirring. Stirring is maintained for 4 hours at room temperature. The reaction medium is evaporated on a water bath under vacuum. The residue is taken up with water and extracted several times with chloroform. The extracts are filtered and evaporated to dryness on a water bath under vacuum. The product is recrystallized in ethanol.

Provenance & Evidence